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Its development program was halted after Phase 2b trials, and it never reached approval as an obesity medication

Symptoms of vitamin B12 deficiency If you think you might have a vitamin B12 deficiency, here are four symptoms to look out for: Fatigue and tiredness Feeling tired all the time is one of the most common symptoms of a vitamin B12 deficiency

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Subsequent work by Heffernan and coworkers (2001) confirmed the peptides effects in obese mouse models, with chronic administration associated with reduced body weight gain and decreased adiposity without concurrent changes in food intake

This means that the term pernicious anaemia does by no means capture the full spectrum of B12 deficiency