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[14] [85] [86] This includes noradrenergic neurons in the locus coeruleus, dopaminergic neurons in the ventral tegmental area, histaminergic neurons in the tuberomammillary nucleus, and serotonergic neurons in the dorsal raphe nucleus

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Potential reproductive or systemic consequences have not been well studied, but theoretical risks include changes to hormonal feedback, timing of ovulation, and unintended effects on sperm or embryo development