Published data from TRIUMPH-1 and TRIUMPH-4 show that discontinuation rates rise with dose
What lifestyle changes should accompany any medication treatment
NICE Symptoms to watch for (because numbers arent everything) Contact your clinician if you notice new symptoms that persist for a couple of weeks, such as: Possible under-replacement (hypothyroid): fatigue, low mood, feeling cold, constipation, dry skin, slower heart rate Possible over-replacement (hyperthyroid): palpitations, tremor, anxiety, sweating, heat intolerance, diarrhoea, trouble sleeping These symptoms can overlap with diet changes and early Mounjaro side effects, so blood tests help clarify whats going on
While helpful, these are "wash-off" products
It adds that appetite suppression typically peaks one to three days after the injection, which is why the article's coordination advice centers on what happens in the days after a dose rather than on pairing the injection itself with a meal