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Notably, subjects with obesity who were treated with retatrutide [12] experienced a reduction of approximately 24% in total body weight, equating to 58 pounds

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Fitzmaurice P.S., Ang L., Guttman M., Rajput A.H., Furukawa Y., Kish S.J

10.1038/s41598-017-06581-6 82

It is metabolized primarily in the liver and other tissues by COMT

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