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Semaglutide-based therapies have been approved by the US Food and Drug Administration for the treatment of type 2 diabetes ( Ozempic / Rybelsus ) and chronic weight management ( Wegovy ), highlighting the major clinical impact of GLP-1Rtargeted therapeutics in metabolic disease [3,4]

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Improved blood sugar control and reduced cravings might contribute to better sleep quality

Since it is able to cross the blood-brain barrier, this form of carnitine is increasingly found in brain cells, where it can have a positive effect on brain functions

In addition the backbone nitrogen of Leu 32* and Trp 33* interact through hydrogen bonds with Asp 34 (CDR1 VH)