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For instance, berberine inhibits endothelial ferroptosis and AS by suppressing ACSL4 expression ( 4.1.2 System Xc -/GSH/GPX4 pathway Ferroptosis is mainly induced by inhibiting glutathione production, with the System Xc -/GSH/GPX4 pathway playing a key role in preventing LPO

The corresponding MFI ( Supplementary Table 4 ) declined to a nadir at 4 h pi and returned to prechallenge values at 72 h pi

N-acetylcysteine attenuates copper overload-induced oxidative injury in brain of rat

placebo])