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Altogether, there is strong evidence that the epigenetic machinery is highly involved in the pathophysiology of NETs

However, the VPA model was specifically selected for its ability to: (1) mimic the gut microbiota dysbiosis observed in ASD patients [45], which genetic models often fail to reproduce [44]

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The CLOCK gene variant rs11133373 was linked to increased BC risk, while the MTNR1A gene variant rs2119882 was associated with reduced risk