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Importantly, a recent retrospective study had found that GLP-1 RAs reduced suicidal ideation in large cohorts of overweight or T2D patients compared to non-GLP-1R agonist anti-obesity or anti-diabetes medications [Reference Wang, Volkow, Berger, Davis, Kaelber and Xu49]

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[1] [4] The medication is administered as a once-weekly subcutaneous injection, with dosing typically initiated at 2.5 mg once weekly for 4 weeks, then increased by 2.5 mg every 4 weeks as needed and tolerated up to 15 mg

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