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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses

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Conclusion In conclusion, the emerging observation that some complications of diabetes are associated with an hyperactivation of RAAS has provided the pathophysiological basis to study the effects of GLP1-RA and SGLT2-i on RAAS to better explain the cardio-reno-protective effect demonstrated by the clinical trials, beyond their role on glucose control

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Frequency: daily or as directed by a physician