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In AD, altered GSH levels in both the brain and blood have been associated closely with disease progression and cognitive decline ( 2 Mechanisms of redox regulation in the CNS 2.1 GSH as an antioxidant in the brain The brain, being one of the most metabolically active organs in the body, requires a large share of oxygen relative to its mass

GCC, a combination of nerve fiber layer, ganglion cell layer (GCL), and inner plexiform layer, is useful for evaluation of structural changes observed in glaucoma 46,47,48

That distinction matters, because it means the size of the resulting pulse still depends on where the endogenous somatostatin rhythm happens to be at the moment of stimulation a source of variability no reconstitution calculation can capture

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