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The findings were published in The New England Journal of Medicine in April 2023

Food intake was weighed daily, with all groups allowed to feed ad libitum

Clinical trials have demonstrated varying degrees of weight loss depending on the specific agent: liraglutide typically achieves 5-8% weight loss over 56 weeks (SCALE trials), while semaglutide has shown approximately 15% weight loss over 68 weeks (STEP trials)