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For instance, it partnered with a health app to help patients manage lifestyle changes alongside drug therapy a move to augment the effectiveness of its new drug treatments

A phase 2 study in TRD (NCT03312894) was planned but withdrawn, and a phase 2 RCT is recruiting to investigate TAK-653 for treatment of adults with MDD (NCT05203341) (Table 1)

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Semin Cell Dev Biol 15(6):665677 Guo W, Schafer S, Greaser ML, Radke MH, Liss M, Govindarajan T, Maatz H, Schulz H, Li S, Parrish AM, Dauksaite V, Vakeel P, Klaassen S, Gerull B, Thierfelder L, Regitz-Zagrosek V, Hacker TA, Saupe KW, Dec GW, Ellinor PT, MacRae CA, Spallek B, Fischer R, Perrot A, zcelik C, Saar K, Hubner N, Gotthardt M (2012) RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing