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Both are serious adverse events of tirzepatide

The primary concern, rapid drops in blood sugar from GLP-1 therapy can temporarily worsen existing DR, which is why it has been highlighted in research

The reason relates to oral cavity preparation

The FDA has established an import alert covering GLP-1 active pharmaceutical ingredients with potential quality concerns, structured as a green list that exempts compliant manufacturers, and has stated the alert does not create new limits on lawful compounding of GLP-1 drugs

You may need to adjust the needle tip a few times so that you can draw up all of the medication in the vial