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By six months, total weight loss is typically 15 to 25 pounds, with higher losses in individuals who started at higher body weights

Childhood and adolescent obesity rates have tripled over the past four decades, and the metabolic consequences of early-onset obesity, including type 2 diabetes, fatty liver disease, and cardiovascular risk factors, are appearing at progressively younger ages

Emerging data indicate that GLP-1 receptor agonists reduce some cancer incidences, possibly through immune regulation and systemic inflammation reduction