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For example, hawthorn fruit polysaccharides alleviate NAFLD in mice by improving gut flora dysbiosis (affecting Lachnospiraceae and Dubosiella ), increasing intestinal acetate levels, and subsequently correcting hepatic amino acid, lipid, and vitamin metabolic disorders

Current evidence suggests that, although this mechanism is present in various animal models, tissue-resident macrophages, derived from embryonic precursors, significantly augment the tumor-associated macrophage population under homeostatic conditions, alongside the bone marrow-derived subset (24)

Safavi, K

[PMC free article: PMC5314421] [PubMed: 28229109] 165

Yes, it is possible to use it on other body areas with uneven skin tone or pigmentation