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Zinc can actually reduce this conversion of testosterone into DHT and thus, reduce the symptoms associated with high testosterone levels

The primary response of a protein to ROS is the oxidation of cysteine and the loss of free thiol groups, [45] resulting in increased thiyl radicals and associated protein cross-linking

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By enhancing mitochondrial energy metabolism and oxidative phosphorylation, GPER increases ATP synthesis

Recent studies have proposed that testosterone inhibits the interaction between microtubule-associated protein tau and glycogen synthase kinase-3 (GSK3) to attenuate tau phosphorylation (Yang et al., 2021