retatrutide blindness Online—Effects of #retatrutide on #body #composition in people with type 2 #diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised trial https://t.co/S7yKZtvcP7 #T2D #weightloss #leanmass Retatrutide | GLP-1R/GIPR/GCGR ligand |

The survodutide comparison is worth noting here too, as survodutide is another glucagon-containing dual agonist that shows strong liver fat effects

and Nilsen, O

b , In vitro stability assay in human plasma

Side effects - primarily gastrointestinal (nausea, vomiting, constipation, and abdominal discomfort) - are well-documented in clinical trial populations and are typically most pronounced during the initial titration phase before the body adapts to rising drug concentrations, which is why the standard-of-care approach involves gradual dose escalation over several weeks or months rather than starting at full therapeutic dose

10.1080/09513590.2018.1505848 Gynecol Endocrinol