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Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates

In fact, several anxiety- and depression-related indicators such as immobility time in the forced swimming test (FST), serum corticosterone level, and hippocampal BDNF concentration were significantly associated with XO activity in the cerebral cortex

JCI Insight 3, 23793708

Nature 497 , 451457 (2013)

3.2.4 Adjuvant therapies Metformin, a first-line antidiabetic drug, is being explored as an adjuvant treatment for generalized psoriasis alongside methotrexate