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After chemical formulas were proposed (see Table S2 in the supplemental material), we searched through a number of databases for the possible compounds and structures, including PubChem ( and ChemSpider ( Finally, their identities were confirmed by comparison to commercially available reference standards (Table S2)

While diet should be optimised to provide a diverse array of antioxidant nutrients, supplementation may be required to address shortfalls that are common in Western-style diets

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maintains circulation to the brain to promote memory and mood, especially in the elderly.(31) Guarana - South American Berry that is one of the best natural sources of caffeine, traditionally used to boost mind energy and physical endurance.(32) Huperzine-A - synthetic alkaloid from Chinese club Moss, used to sustain acetylcholine levels and shown to help with memory and degenerative brain concerns.(33) Kanna (Sceletium tortuosum) - South African herb shown in research to help with mental alertness in seniors with brain degeneration and cognitive deficits.(34) Kava Kava - psychoactive root herb used in traditional South Pacific ceremonies