This systemic inflammation, akin to the processes described in schizophrenia, can traverse the blood-brain barrier or transmit via vagal afferents, subsequently activating microglia and exacerbating neuroinflammatory processes while impairing prefrontal cortex-mediated executive functions including decision-making and emotional regulation (270)
(Also worth noting: Their levels of ghrelin, a hunger hormone, significantly decreased during this period.) 3
doi: 10.1016/j.bmc.2020.115464 8 ChenZ.LiZ.LiF.WangM.WangN.GaoX.-D
If fatigue persists despite these interventions, or if it is accompanied by other concerning symptoms, further medical evaluation is warranted to exclude alternative diagnoses
These include improper storage and handling of the product after it leaves our hands, diagnosis, dosage, method of administration and biological differences in individual patients