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With this in mind, we explored the GEP44-mediated internalization of Y2-R and internalization and recruitment of -arrestin-2 at GLP-1R (Fig

Other brain regions with GLP-1 receptor expression include: Ventral tegmental area and nucleus accumbens (reward and motivation circuits) Amygdala (emotional processing and stress responses) Prefrontal cortex (executive function and decision-making) Substantia nigra (motor control, relevant to Parkinson's disease research) This widespread distribution suggests that GLP-1 influences diverse neurological functions beyond appetite regulation

V., Abramovitz, L., et al

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