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In addition to the current clinical interventions available to manage APAP hepatotoxicity, including gastrointestinal track decontamination, NAC administration and liver transplantation, the improvement of mitophagy may stand as a promising novel approach for the management of APAP hepatotoxicity

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Cazzola M., Calzetta L., Page C., Jardim J., Chuchalin A.G., Rogliani P., Gabriella Matera M

It can be sequestered and cleared off using hemopexin, as its administration reduced tissue damage and lethality [112]

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