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Symptoms of a serious allergic reaction may include: swelling of your face, lips, tongue, or throat, fainting or feeling dizzy, very rapid heartbeat, problems breathing or swallowing, and severe rash or itching Talk with your health care provider if you are not sure if you are pregnant or planning to become pregnant

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Persistent nausea that interferes with hydration, nutrition, or daily function should be discussed with a healthcare professional rather than assumed to be a normal adjustment symptom

Effect of Food Food decreases the extent of and slightly delays the absorption of metformin, as shown by approximately a 40% lower mean peak plasma concentration (Cmax), a 25% lower area under the plasma concentration versus time curve (AUC), and a 35-minute prolongation of time to peak plasma concentration (Tmax) following administration of a single 850-mg tablet of metformin HCl with food, compared to the same tablet strength administered fasting

(The Financial Times has an excellent story on the scientific and economic race to make these new pills