1st day of semaglutide for weight loss | Blog 𝘈𝘳𝘦 𝘺𝘰𝘶 𝘳𝘦𝘢𝘥𝘺 𝘵𝘰 𝗟𝗢𝗦𝗘

Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis

PMID: 26388782

10.1016/s0968-0896(00)00294-7 76 LukaszukA.DemaegdtH.FeytensD.VanderheydenP.VauquelinG.TourwD

Indian barberry root extract (Berberis aristata DC.), white mulberry leaf extract (Morus alba L.), capsule shell: hydroxypropylmethylcellulose, corn starch, corn fiber, bacterial strain: Lactobacillus paracasei D3.5 (heat-inactivated), chicory root extract (Cichorium intybus L.), anti-caking agent: magnesium salts of fatty acids, chromium picolinate

In the organoids, cell cycle and early developmental genes were enriched