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To maintain its effectiveness, B12 needs to be kept in a cool, dry place, far away from direct sunlight

De Lorgeril M, Salen P, Paillard F, Laporte F, Boucher F, de Leiris J (2002) Mediterranean diet and the French paradox: two distinct biogeographic concepts for one consolidated scientific theory on the role of nutrition in coronary heart disease

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An ideal strategy should integrate imaging such as quantitative MRI parameters, fluid aspiration measuring MDA, 4-HNE, iron metabolism indicators, and GPX4-related protein/nucleic acid levels, and advanced omics analyses to build a comprehensive risk assessment system for predicting ferroptosis activity and treatment response (Lotz et al., 2013)

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