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Subject demographics (for example: age, sex, self-identified race), lab values (for example: HbA1c, BMI, liver enzymes), and some medication information (GLP-1 M, other drugs used to treat T2D, and NSAIDs) and presence or absence of diabetes-associated complications (for example: chronic kidney disease, cardiovascular disease) were extracted as prediction features

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Overall, further studies are needed to dissect the specific molecular signals downstream of FN that drive the shift of mature MCs toward less differentiated states and to delineate the respective contributions of individual signaling pathways in ECM-mediated responses