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Circulation 145:e895e1032 Kosiborod MN, Abildstrm SZ, Borlaug BA et al (2023) Design and baseline characteristics of STEP-HFpEF program evaluating semaglutide in patients with obesity HFpEF phenotype

Focus on Protein First at Meals The Science: Protein is widely considered the most satiating macronutrient, and recent clinical research clarifies why: it has a direct hands-on effect on your guts endocrine system

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Matrisome dysregulation in astrocytes co-cultured with neurons was linked to elevated chemotaxis, glial activation, and lipid biosynthesis, mirroring altered matrisome signaling observed in human brain tissue (Tcw et al., 2022)

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