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Mattioli S, Dimauro C, Cesarani A, Dal Bosco A, Bartolini D, Galli F et al (2022) A dynamic model for estimating the interaction of ROSPUFAantioxidants in rabbit
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Receptor Downregulation Findings and Study Design Implications A well-documented finding in the research literature is that continuous IGF-1 receptor activation leads to receptor downregulation after approximately four to six weeks, reducing cellular responsiveness to further stimulation
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