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Multiple MC1R variants , the R151C, R160W, and D294H variants strongly associated with red hair and melanoma risk , show impaired Gs coupling and reduced cAMP signalling responses to MC1R agonist stimulation

176 The remaining cysteine circulates mostly as cystine (2530%, 4050 M) and the low abundance pool constituted by reduced cysteine

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Fibroblasts are considered to play an important role in skin rejuvenation

Polysaccharide extracted from Phellinus igniarius attenuated hyperuricemia by modulating bile acid metabolism and inhibiting uric acid synthesis in adenine/potassium oxonate-treated mice