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I have read that some people try spacing out their doses or try using a smaller amount from their pen

Alpha Lipoic Acid (ALA):Promotes energy metabolism and helps reduce oxidative stress

A randomized double-blind multi-center trial of hydrogen water for Parkinson's disease: protocol and baseline characteristics

During the protocol, no lesion occurred on the injection area and the patient continued to use the drug in one injection per application in the following days without any reaction

Since the response is dose-sensitive and even biphasic, careful studies test a spread of concentrations across several orders of magnitude rather than betting on one number