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Lancet 391 , 11861196 (2018)

Leptin Leptin is a 167 amino acid anorexigenic peptide primarily produced by white adipose tissue (375), regulates body fat mass (376) by feedback inhibition of the appetite centers of the hypothalamus (377)

Therefore, MI reduces androgen levels (testosterone and androstenedione), corrects the LH/FSH ratio, restores normal menstrual cycles and induces ovulation, thereby facilitating spontaneous pregnancies by adequate luteal phase progesterone production [10]

Pediatr Res 6:949954 Deganuto M, Cesaratto L, Bellarosa C, Calligaris R, Vilotti S, Renzone G, Foti R, Scaloni A, Gustincich S, Quadrifoglio F, Tiribelli C (2010) A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein