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In addition to cognitive benefits, aerobic exercise also affects non-hallmark AD pathologies by reducing oxidative stress, suppressing neuroinflammation, and improving glucose hypometabolism (243)

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The fatty acids have to undergo activation in the cytosol by getting converted to fatty acyl CoA to pass though the mitochondrial membrane with the help of carnitine (present as L-carnitine , the active stereoisomer) after which they undergo -oxidation in the mitochondria

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