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Adding a GLP-1 drug to type 1 diabetes management can create dangerous drug interactions and unpredictable blood sugar fluctuations without providing the intended benefit

IGF-1 is best thought of as a maturation hormone because it not only promotes cell proliferation, but differentiation as well

yet these agents may favor an increase of lean mass and mimic an energy deprivation state with increased ketogenesis (i.e., BHB) through increased circulating GH levels ( Figure 1 )

Munaf M, Pellicori P, Allgar V, Wong K: A meta-analysis of the therapeutic effects of glucagon-like Peptide-1 agonist in heart failure