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Wahab et al 7 conducted double-blind randomized controlled clinical trial evaluated the efficacy of topical and oral glutathione as skin-whitening agents

Data availability No datasets were generated or analyzed during the current study

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By acting as a carrier and regulator of bioavailable copper, GHK-Cu plays a role in maintaining metal homeostasis and influencing downstream pathways linked to cellular growth, differentiation, and tissue remodelling

However, these antibodies do not appear to impact efficacy or cause significant allergic reactions, suggesting they are neutralizing rather than pathogenic