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Familial aggregation of autoimmune diseases is commonly observed, with ankylosing spondylitis exhibiting particularly high rates of prevalence among first-degree relatives, reaching up to 1030% compared with the general population [25]

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Age Young age A number of studies have investigated the difference in paracetamol metabolism between neonates, children and adults and whether this affects their propensity to paracetamol-induced toxicity

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