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No dose adjustment is required based on renal function, but patients with severe renal impairment should be monitored closely, particularly if experiencing severe gastrointestinal adverse events

Targets 12 , 14971507 (2008)

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Ambulatory blood pressure monitoring used in this study included blood pressure measurements every 30 minutes during the day and every hour at night, providing a more comprehensive assessment of blood pressure than in-office or daily home blood pressure measurements

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