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the macules may be present on the shaft of the penis or on the glans penis The presence of numerous melanotic macules on the body may be associated with a variety of syndromes including Carney complex, Peutz-Jeghers syndrome, and LEOPARD syndrome

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Evidence on NAC suggests context-dependent effects, with supplementation improving glutathione availability, fatigue resistance, and exercise performance in individuals with low baseline glutathione, while results remain inconsistent in healthy populations

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