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Obesity: identification, assessment and management (CG189) scope reference

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Lifestyle Changes for Effective Weight Loss While this medication can be a powerful tool in weight loss management, it is important to note that it should be used in conjunction with lifestyle changes for optimal results

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In high-glucosechallenged retinal pigment epithelial cells, PCs activate the p53/mTOR autophagy pathway, lowering apoptosis-related factors (e.g., Bax, Caspase-3, LC3-II/LC3-I, and phosphorylated p53) and elevating the levels of survival proteins (Bcl-2, p62, and phosphorylated mTOR) (Li et al., 2022)

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