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While the majority of patients on GLP-1s take them at the standard doses, more and more people are starting to talk about microdosing instead

Nevertheless, preclinical research from cellular and animal studies suggest collagen peptides may support gut integrity and reduce inflammation related to increased intestinal permeability

These cases are being handled separately because the medical science involved is distinct from the gastrointestinal claims, and because the defendants include both Novo Nordisk (Ozempic, Wegovy) and Eli Lilly (Mounjaro, Zepbound)

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Interestingly, RYGB controls 5-HT 2A receptor availability in the ventral striatum in rats [112], suggesting that GLP-1R agonists and bariatric surgery may both target the midbrain serotonergic system to exert their inhibitory effects on energy balance