10.1152/ajpendo.00551.2012
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Rag proteins mediate lysosomal recruitment of mTORC1, which is subsequently activated by Ras homologs enriched in the brain (Rheb) present on the lysosomal membrane
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For context, real-world data on oral semaglutide from Rybelsus doses up to 14 mg showed more modest results, around 5.7% weight reduction
