This peptide was first isolated and identified in the 1990s by Croatian researchers, who observed its remarkable protective properties on gastrointestinal tract tissues
BCAT1 expressed in the cytoplasm was highly expressed in human epidermal growth factor receptor 2 positive (HER2 + ) breast cancer, while BCAT2 expressed in the mitochondria tended to be highly expressed in estrogen receptor-positive (ER + ) breast cancer
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Mogi and Nagatsu, 1999) or normal (Rota et al., 2006), and TGF-2 increased (Vawter et al., 1996)