Typically, the BeWo cell line has successfully been utilized in exploring drug transportation
It is used in aesthetic dermatology due to its anti-photo aging effect by increasing collagen type 1 and also in the treatment of cellulite due to its anti-inflammatory activity and drainage that help regulate microcirculation [32]
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Furthermore, several terms upregulated in old indicate active metabolic detoxification processes (for example, alcohol metabolic process and cellular aldehyde metabolic process), as well as oxidative stress defense (for example, glutathione metabolic process) and remodeling of the extracellular matrix (for example, uronic acid metabolic process, extracellular matrix organization and biological adhesion)