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GLP-1R activation and multifunctional effects GLP-1 has its main effects through the activation of GLP-1R which belongs to the family of G-protein coupled receptors

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Relevant combinations of LSD1 inhibitors with cell therapy infusions and immune checkpoint blockade have shown efficacy in pre-clinical solid tumor models, reinforcing a need to understand how these drugs would impact T- and NK cells

Bartolo L, Afroz S, Pan YG, Xu R, Williams L, Lin CF, et al