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Characteristic muscle pathology with pronounced lipid storage and global decrease of COX and/or SDH histochemical staining has been reported [39]

4, 6 Although pre-endoscopic empiric therapy with PPI is recommended for all patients, this is based on the excellent safety profile of PPIs rather than evidence regarding their efficacy

Kim MH, Jee JH, Park S, Lee MS, Kim KW, Lee MK (2014) Metformin enhances glucagon-like peptide 1 via cooperation between insulin and Wnt signaling

Kamalmaz N, Ben Bacha A, Alonazi M, Albasher G, Khayyat AIA, El-Ansary A

Its mechanism is thought to specifically stimulate lipolysis (the breakdown of fat) without affecting insulin sensitivity or cell proliferation