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Impressively, the 5-Amino-1MQ-treated mice did not show adverse effects during the experiment

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Epitalon once more demonstrated a diminishing influence on the activity of these enzymes

Entinostat (Ent), as a Class I HDAC inhibitor, downregulates pro-fibrotic genes Acta2 and Col1a1, as well as the pro-inflammatory factor LIF, by inhibiting the SRF-FOXM1 transcriptional axis at concentrations of 510 M in vitro , thereby blocking CAF activation and weakening the STAT3 pathway in tumor cells (112)