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Disruptions to this cycle can shorten the growth phase and prolong the resting phase, leading to gradual thinning

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In line with this idea, activating oxytocin receptor (OXR)-expressing vagal afferents, which also form IGLEs in the muscular wall of the small intestine in mice, robustly suppresses food intake [31]

Patients interpret same dose as no change. But the pharmacology tells a different story

Patients should be advised to seek prompt medical evaluation for severe or persistent gastrointestinal symptoms, vision changes, unusual neck swelling or hoarseness, or severe constipation with abdominal distention