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Proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE ( partner repository with the dataset identifier PXD046243

78 However, the demonstration of endothelial dysfunction in the presence of increased expression of eNOS indicates that the capacity of the enzyme to produce NO may be limited, and the concept that eNOS itself can be a superoxide source and thereby contributes to endothelial dysfunction provides a further explanation to this observation

In October 2023, the U.S