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While some recent studies have suggested such a relationship, further studies are required to conclusively determine if an association or causal relationship exists and/or whether inflammatory bowel disease risk may be linked to the presence of severe acne itself. In summary, there is no current definitive evidence to support a link or risk of inflammatory bowel disease from Accutane

complications (fistula, abscess) may be principal if the complication is the primary reason for admission

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High humidity impairs sweat evaporation, forcing the body to produce more sweat to maintain core temperature