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467 However, a 12-month phase 2b (NCT094546) study of dietary spermidine supplementation revealed no changes in memory or biomarkers in older adults, possibly because of the lower spermidine dose (0.9 mg/day)30

Half of the people who were studied had histones that were too acetylated in their peripheral blood mononuclear cells (Su et al., 2011)

For example, some endogenous proteins in the matrix share similar hydrophobicity with bovine insulin, potentially interfering with analysis during the pretreatment process

Important considerations: If you have kidney disease, consult your healthcare professional before increasing protein intake or using protein supplements

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