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GLP-1 helps improve insulin sensitivity and may improve insulin resistance in some patients

Efficacy and Safety of Once-Weekly Dulaglutide Versus Insulin Glargine in Mainly Asian Patients With Type 2 Diabetes Mellitus on Metformin and/or a Sulphonylurea: A 52-Week Open-Label, Randomized Phase III Trial

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When you combine the two substances, you may be at an increased risk of these side effects: Impaired judgment Worsened coordination Severe drowsiness or dizziness Its also important to remember that each of these substances can increase suicidal thoughts and actions, says Daniel Krinsky, R.Ph., founder of PGx101, a company that provides pharmacogenomics training

The article also says a PCP should establish a schedule for follow-up labs such as kidney function and liver enzymes alongside those clinical check-ins